SAN DIEGO – July 6, 2005 – Verus
Pharmaceuticals, Inc., a pediatric-oriented company dedicated to identifying,
developing and delivering solutions to address the unmet medical needs
of children and those who care for them, today announced it has acquired
exclusive, worldwide rights to Twinject® from Hollister-Stier
Laboratories LLC. Twinject, a novel epinephrine auto-injector indicated
for the emergency treatment of severe allergic reactions (anaphylaxis),
was approved by the U.S. Food and Drug Administration (FDA) in 2003;
two dosages are now approved for self-administration (0.3 mg and 0.15
mg). In addition to Twinject, Verus has acquired rights to other intellectual
property and assets, including complementary and next generation device
designs and on-going development programs.
“There are significant unmet medical needs for those individuals
at risk for anaphylaxis and, unfortunately, no advancements in self-administered
treatment options have been commercialized in the U.S. since the early
1980s,” said Robert W. Keith, President and Chief Operating Officer
of Verus. “Twinject is the first and only product approved by the
FDA that contains two doses of epinephrine in a single device. This is
an important feature of Twinject, as published studies have demonstrated
that more than one dose of epinephrine may be required in many situations
to properly address the allergic reaction, with the second dose often
needed within 5-10 minutes after the first dose. As such, we are eager
to bring this novel product line to market and are committed to working
closely with patients, caregivers, and advocacy groups to develop additional
products that address other unmet medical needs for those at risk.”
“The acquisition of Twinject allows Verus the opportunity to establish
a leadership position in an attractive, high growth market,” said
Todd C. Davis of Paul Royalty Fund. “We look forward to working
with the Verus management team to launch Twinject and to build a comprehensive
anaphylaxis franchise on a global basis.”
About Anaphylaxis
Anaphylaxis is a severe, life-threatening systemic allergic reaction
triggered by exposure to one or more various antigens, including foods,
insect stings, drugs, and latex products. Up to 43 million people in
the U.S. alone are at risk for anaphylactic episodes, and underlying
incidence rates are expected to continue increasing in future years.
Up to eight percent of children have food allergies, with allergies to
peanuts and tree nuts among children having doubled in the past five
years. The timing, location, pattern (including onset, severity and length)
and specific treatment requirements for each future anaphylactic episode
cannot be predicted in advance.
About Verus
Verus Pharmaceuticals is dedicated to improving the lives of children
and those who care for them. Verus is building a portfolio of products
for the unmet medical needs of children through acquisitions and alliances,
with an initial focus on the treatment of asthma, allergies, and related
diseases and conditions. Verus is differentiated by its pediatric orientation
and its strong financial position and experienced management team, which
allows the company to capitalize on an extensive network to build its
product portfolio and pursue complementary transactions. The company’s
rigorous, disciplined approach to strategic decision-making and core
competencies in development and commercialization is expected to provide
significant value to its partners. More information about Verus is available
on the company’s website at www.veruspharm.com.
Forward-Looking Statements
Verus Pharmaceuticals cautions you that statements included in this
press release that are not a description of historical facts may be forward-looking
statements. The inclusion of forward-looking statements should not be
regarded as a representation by Verus that any of its plans will be achieved.
Actual results may differ materially from those set forth in this press
release due to the risks and uncertainties inherent in Verus’ business
including, without limitation, statements about: its ability to identify
appropriate acquisition, licensing, or co-development and/or promotion
candidates in the future or be able to take advantage of the opportunities
it identifies; difficulties or delays in developing, obtaining regulatory
approval, manufacturing and commercializing its products; unexpected
performance or side effects of its products that could delay or prevent
development or commercialization, or that could result in recalls or
product liability claims; the scope and validity of patent protection
for its products; competition from other pharmaceutical companies; and
its ability to obtain additional financing to support its operations.
All forward-looking statements are qualified in their entirety by this
cautionary statement and Verus undertakes no obligation to revise or
update this press release to reflect events or circumstances after the
date hereof.
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